ĭisulfiram, a drug sometimes given as treatment for alcoholism, induces effects similar to alcohol flush or hangover causing the disulfiram-alcohol reaction. Many cases of alcohol-induced respiratory reactions, which involve rhinitis and worsening of asthma, develop within 1–60 minutes of drinking alcohol and are due to the same causes as flush reactions. People who experience the reaction may be less prone to alcoholism as it tends to discourage them from drinking. People affected by this condition show greater reduction in psychomotor functions on alcohol consumption than those without. Other effects include "nausea, headache and general physical discomfort". The most obvious symptom of alcohol flush reaction is flushing on a person's face and body after drinking alcohol. Signs and symptoms The back of an East Asian man showing alcohol flush reaction. The condition may be also highly prevalent in some Southeast Asian and Inuit populations. The reaction is also termed "Asian flush" due to its frequent occurrence in East Asians, with approximately 30 to 50% of Chinese, Japanese, and Koreans showing characteristic physiological responses to drinking alcohol that includes facial flushing, nausea, headaches and a fast heart rate. However, it has also been associated with an increased risk of esophageal cancer in those who do drink. This syndrome has been associated with lower than average rates of alcoholism, possibly due to its association with adverse effects after drinking alcohol. The reaction is the result of an accumulation of acetaldehyde, a metabolic byproduct of the catabolic metabolism of alcohol, and is caused by an aldehyde dehydrogenase 2 deficiency. Īlcohol flush reaction is a condition in which a person develops flushes or blotches associated with erythema on the face, neck, shoulders, and in some cases, the entire body after consuming alcoholic beverages. A 22-year-old East Asian man who is ALDH2 heterozygous showing the reaction. Before (left) and after (right) drinking alcohol. You may report side effects to the FDA at 1-80.Asian flush syndrome, Asian flush reaction, Asian glow, Asian red face glowįacial flushing. If you notice any other effects, check with your healthcare professional.Ĭall your doctor for medical advice about side effects. Other side effects not listed may also occur in some patients. White patches in the mouth or throat or on the tongue Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less commonīad, unusual, or unpleasant (after) tasteĭiscoloration of the tooth (brown, yellow, or gray staining) Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Some side effects may occur that usually do not need medical attention. Sores, ulcers, or white spots in the mouth or on the lips Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue Check with your doctor immediately if any of the following side effects occur: Incidence not knownĪbdominal or stomach cramps or tendernessīlistering, peeling, or loosening of the skinĭiarrhea, watery and severe, which may also be bloody
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